Ointment Psoriasis what is ointment effective for the treatment of Psoriasis?

People with the diagnosis "psoriasis", the first-Hand knowledge, how much depends on the correct selection of the drugs. This disease does not forgive mistakes in the treatment and neglect to their health. An important role in dealing with the symptoms of psoriasis, the well-chosen external therapy and timely treatment play. An important principle for the selection of the scheme of treatment, especially in the early stages of the development of Psoriasis, is the principle of "do no harm" treatment should not be an attack on the health of the skin, provoking the emergence of undesirable effects in the Form of atrophy of the skin or of the syndrome. Because the main goal of therapy is to prolong the periods of peace and the health of the skin, without the sudden and painful relapses and exacerbations.

Ointment of psoriasis

Hormonal psoriasis ointment to treat or to kill?

Frequent group external agent for the treatment of psoriasis are ointments on the Basis of special hormones. These substances have the property to reduce to suppress the activity of the immune system, the inflammation. Therefore, in the case of severe exacerbations of Psoriasis steroids administered systemically, in the Form of tablets or injections. However, this approach carries with it serious side effects: the therapy changes the hormonal background of the organism, and the abolition of the drugs.malfunction of the endocrine and cardiovascular Systems

Topical steroids (external hormonal agents), the hazardous properties deprived of systemic preparations with a basis of hormones: the effect shows up only at the point of application. Advantage of the rapid effect: after just a few minutes after applying the patients a decrease the itching reports, and in the next few days, significantly reduced redness in the psoriatic Plaques, it stops their growth and molting.

But, unfortunately, side effects are typical for the use of topical steroid not less serious: due to the lowering of immunity at the site of application, the skin is thin and discolored, the risk of the accession of secondary infection. It is undisputed that complicates the treatment. The most serious consequence of the application of topical steroids on the development of habituation. In the consequence of other media (Yes, and even topical steroids) will not change, provoking constantly, sometimes stronger relapses after discontinuation. Therefore, the sale of topical steroids in Europe and the United States is prohibited without a prescription. Independent and uncontrolled use of these funds in relation to the category of potent, is not permitted.

It is important to know! Addison's disease — a condition caused by long-term administration of glucocorticosteroids. To produce In response to the hormonal therapy in addition to kidneys Cortisol and other steroids, what is palpitations in symptoms such as muscle weakness, weight loss and loss of appetite, low blood pressure, dehydration, a heart and a permanent feeling of fear. In the case of Addison disease the doctors are not always able to restore the function of the adrenal glands, so that patients with life-long prescribe hormone therapy.

Most of the funds on the basis of topical steroids is inexpensive and sold without a prescription, so that cases of abuse of this kind are the treatment of Psoriasis often. In the meantime, dermatologists do not recommend the use on topical steroids with large-scale (more than 20% of the skin surface) areas of destruction, and also such means of skin folds and places of diaper dermatitis can be applied on sensitive areas of the body — face, neck,. It is desirable and in General the idea to give up hormonal ointments and creams to apply without a doctor's prescription: it is capable of reducing the effect of primary treatment, to cause harm to the health and provoke an attack of severe exacerbations of Psoriasis.

The most common hormonal creams and ointments on the basis of the following substances:

  • Betamethasone;
  • Hydrocortisone;
  • Mometasone Furoate;
  • Methyl prednisolone;
  • Triamcinolone;

Traditional non-hormonal ointment for the treatment of Psoriasis: it will not be worse, but better?

In view of the serious side effects of hormonal creams and ointments, many patients prefer to treat psoriasis with the help of less "aggressive" medication. Some of them the heritage of the folk medicine and traditional recipes of the treatment of the skin, popular in the past.

The benefits of traditional treatment without hormones Psoriasis is due to be the Benchmark with hormonal means of security, cheapness and the lack of serious side effects. The disadvantages — the use of different (often low) degree of effectiveness and, in some cases, — allergic reactions, that develop in patients on components of the various funds.

Signs of psoriasis
  • Naftalan, the ichtiolowaja, dermatological, ointment on the Basis of tar have anti-inflammatory and antiseptic effect. But some of them should not be used in advanced stages of Psoriasis, and on the large areas of the lesion, while others (e.g., tar ointment) have a certain effect, therefore, it is not recommended for use in combination with phototherapy. In addition, the prolonged use of these agents increases the likelihood of developing skin cancer. Traditional ointments also have a pretty pungent odor and can soil clothing, in connection with what is not very convenient to use.
  • Special substances, anti-inflammatory and anti-microbial effect, cause a Peeling, increased dead cells, accelerates the healing process of psoriatic Plaques. Among the possible side effects — the risk of inflammatory reactions, burning sensation, and pigmentation of the surrounding healthy skin (discoloration of healthy skin and hair in brown).
  • Phyto-products (ointments and creams based on Aloe, elecampane, celandine, sage, and other herbs) have an anti-inflammatory and healing actions, hinder the development of skin infections. AIDS in the treatment of psoriasis, supplements the effect of the basic treatment.
  • Moisturizers (Baby creams and oils, cosmetics) are also complementary in the treatment of psoriasis and help in the fight against dryness and the feeling of tightness of the skin. They are used in combination with drugs to improve the effect of therapy.

Non-hormonal ointments and creams with a pronounced healing effect clinically proven

Of particular note is the group of nonhormonal drugs, their efficacy in the topical treatment of Psoriasis confirmed in the clinical studies. In contrast to ointments and creams from the previous group, the mechanism of action of these drugs can be examined in Detail. You have the advantage, compared to the hormonal agents in connection with a higher safety profile. But also in the treatment with these agents needs to clear application instructions and to know about possible contraindications.

  • Pimecrolimus has high anti-inflammatory activity. However, you should know that in the case of a bacterial or fungal infections of the skin-application of funds on the basis of Pimecrolimus is recommended, after healing of the infection. In the case of an unattended use of Pimecrolimus of local immunosuppression in the skin (inhibition of local immunity), that increases the risk of accession of secondary infection to the affected areas of the skin. may cause So in the US, for example, it is recommended that Pimecrolimus is only used as a drug for "second line" treatment, that is, without the effect of the other means of therapy. Pimecrolimus is for use by children under two years of age.
  • Kaltsipotriol is a synthetic analogue of Vitamin D3. Its effect is based on the increase in the level of calcium in the cells of the skin, normalizes the rate of cell division and promotes the Resorption of psoriatic Plaques. Since calcipotriol is a hormonal agent (after a series of biochemical reactions is transformed into an active hormonal metabolism metabolite), there are a number of restrictions on its use. In particular, calcipotriol does not apply if he has more than 30% of the surface of the skin because of the risk of hypercalcemia. The latter can cramps, heart arrhythmia, and muscle. To not recommend the application of calcipotriol on the sensitive skin areas (face, neck, wrinkle). On the Basis of this active substance have age restrictions. Calcipotriol is also not suitable as a tool in the case of treatment by means of phototherapy, as under the action of UV radiation causes sensitivity to light and leads to the development of burns of the skin.
  • Pyrithione zinc. Because of the proven effectiveness and safety of the treatment, preparations for the treatment of Psoriasis on the Basis of this active substance, the Golden middle belong to the category "". Zinc is a organic and natural medicine for the treatment of skin diseases. Its concentration in the healthy epithelium of the people is about 20% of the total content in the body, and a deficiency of this precious metal is accompanied by a variety of lesions of the skin and deterioration of wound healing. Drugs with the active zinc (pyrithione zinc) have a number of specific properties, anti-inflammatory, antibacterial, antifungal), to help reduce itching of the skin skin, the production of ceramides (lipids), leading to a recovery of the barrier function. Medium pyrithione zinc to activate the so-called apoptosis (natural programmed death) of diseased skin cells and inflammation, thereby activating the natural renewal of the cells of the epithelium, resulting in the flaking and removal of Psoriasis Plaques. Studies have proven that the active zinc is comparable with hormonal agents efficiently, and a good safety profile, there is practically not from the surface of the skin absorbs, has no irritating and harmful effect.

Ointment or cream?

Many of the above mentioned medicines are available in the Form of ointment and as a cream. How to choose the most appropriate Form?

  • Ointments have a more dense and fatty texture, which allows for a drug for a long time on the surface of the skin, especially if it is applied under the bandage.
  • The cream has a soft texture, lighter and absorbed faster, causing you to apply, so that the skin is open, not with a Bandage, and without fear on your hands or clothes. In General, the cream has a pleasant smell, which is also important in the daily apply.
  • In contrast to ointments, cream, and, to a lesser extent, has no irritating effect, therefore, it is more suitable for the application on the face, flexor surfaces of the joints, the areas with increased sensitivity. Also, the ointment is not suitable for application on moist areas of the affected skin with the liquid discharge. The cream in this sense, is more than versatile.
  • Traditionally, ointment for Psoriasis are wider, but this imbalance will slow down gradually — in the market there are more and more new dosage forms in the Form of creams, Gels, and aerosols for easy application, and is particularly suitable for application to hard-to-reach places (such as on the scalp).
Psoriasis Treatment

We are looking for the Balance between quality and price

We try to summarize these data in the Form of a table:

The group of the drug

Active ingredient

Action

Possible restrictions and side effects

Hormonal creams and ointments

Betamethasone

Anti-inflammatory, anti-Allergy (including itching), and edematous effect. Hydro cortisone, methyl prednisolone, and other means also have a certain effect (overwhelming local immunity of the skin).

1. It is not recommended long-term (longer than 5 days) and often. 2. Trigger the development of local complications:

  • Discoloration and metabolic disorders in the skin;
  • the syndrome;
  • immunodepressivne effect can lead to secondary infection of the skin.
  • Cons:
  • for use in areas with sensitive skin (face, neck, folds);
  • for large areas of the lesion (more than 30% of the skin).

Mometasone Furoate

Hydrocortisone

Glucocorticoid Agents

Methylprednisolone

Triamcinolone

Non-hormonal traditional means

  • Oil
  • Sulfur
  • Ihtiola
  • Solidol
  • Tar

You have an anti-inflammatory and antiseptic effect.

  • A relatively low efficiency and do not apply on bacterial-fungal agent (in the case of a secondary infection on the skin).
  • Inconvenient for the application (castrated several times a day, often under the Association, require very lengthy therapies, stains clothes and an unpleasant odor).
  • Irritation and dryness of the skin as well as allergic reactions.

Substances active in the desquamation of dead cells from the skin surface:

  • dithranol
  • Sulfur and salicylic acid

Increased desquamation cause of dead skin cells, anti-inflammatory and anti-microbial effect.

Cause inflammatory reactions, burning sensation, and the pigmentation of the surrounding healthy skin (discoloration of healthy skin and hair in brown).

Non-hormonal drugs

Pimecrolimus

Possesses anti-inflammatory activity.

  • Not recommended for use in the event of a bacterial or fungal infections of the skin.
  • Local cause immunosuppression in the skin (reduced local immunity).
  • Is contraindicated in children up to two years.

Calcipotriol

Is a synthetic analogue of Vitamin D3, promotes the Resorption of psoriatic Plaques.

  • Not recommend:
  • apply, if he has more than 30% of the surface of the skin because of the risk of hypercalcemia;
  • apply on sensitive skin areas (face, neck, wrinkle, scalp);
  • combined with the method of photo-therapy in connection with danger of burns to the skin.
  • In contrast to younger than six years of indicated for patients.

Pyrithione zinc

Has a complex effect:

  • anti-inflammatory;
  • itching;
  • Protection before the accession of the infection;
  • the activation of the natural cellular renewal of the skin cells to eliminate psoriatic Plaques;
  • Restoration of the barrier function of the skin.
  • A high safety profile.
  • No restriction on the duration of application and the surface application.
  • Has no side effects (except in cases of individual intolerance).
  • Approved for children a year.

Psoriasis — a chronic disease so each Patient is important for optimal medication, combined with the high efficiency and a Minimum of side effects (and it is advisable, for a reasonable price). And remember: before you start to use any means, read the instructions, all the possible contraindications and side effects, and a consultation with your doctor. This will help to achieve the best results without damage to health.

Ointments against psoriasis

Timely treatment in Psoriasis is an important factor for success. Remember that the sooner you begin to treat Psoriasis, the less likely it is that you can grab ever is to "heavy artillery" — hormonal agents.

03.10.2018